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DeCS
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Descritor Inglês:
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DNA Gyrase
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Descritor Espanhol:
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Girasa de ADN
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Descritor Português:
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DNA Girase
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Sinônimos Inglês:
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DNA Gyrase A Subunit
DNA Gyrase B Subunit
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Categoria:
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D08.811.399.403.741.149
D12.776.097.237
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Definição Inglês:
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A bacterial DNA topoisomerase II that catalyzes ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. Gyrase binds to DNA as a heterotetramer consisting of two A and two B subunits. In the presence of ATP, gyrase is able to convert the relaxed circular DNA duplex into a superhelix. In the absence of ATP, supercoiled DNA is relaxed by DNA gyrase. |
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Combinados Inglês:
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DNA Gyrase/antagonists & inhibitors use Topoisomerase II Inhibitors
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Nota Histórica Inglês:
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2002; use DNA TOPOISOMERASE (ATP-HYDROLYZING) 1994-2001, use DNA GYRASE 1980-1993; for GYRA PROTEIN use DNA TOPOISOMERASE (ATP-HYDROLYZING) (NM) 1992-2001; GYRB PROTEIN use DNA TOPOISOMERASE (ATP-HYDROLYZING) (NM) 1991-2001
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Qualificadores Permitidos Inglês:
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Número do Registro:
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36089
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Identificador Único:
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D027081
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Ocorrência na BVS:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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